Cavaliers vs. Bulls NBA expert prediction and odds for Wednesday, Feb. 28 (Target total bet)

Betting odds, pick and prediction for the Chicago Bulls' matchup with the Cleveland Cavaliers on Wednesday night.
Chicago Bulls guard Coby White (0) drives to the basket.
Chicago Bulls guard Coby White (0) drives to the basket. / Ken Blaze-USA TODAY Sports

The Chicago Bulls are looking to protect home court on Wednesday against their division rival – the Cleveland Cavaliers – who have been on fire since the start of 2024. 

The Cavs won the last meeting between these teams, outlasting Chicago in a three-point victory at home. This game is in Chicago, and that’s a good sign for the Bulls, who have thrived when set as underdogs at the United Center. 

This is the second game of a back-to-back for the Cavs, who played the Dallas Mavericks on Tuesday night and won on a crazy buzzer beater by Max Strus. 

Chicago also played on Tuesday night, turning in a major clunker in a loss to the Detroit Pistons. Can Chicago bounce back as a home dog on Wednesday? 

If you’re looking to bet on any game in the NBA tonight, FanDuel Sportsbook has an amazing promotional offer. New users who sign up with the link below and wager $5 will receive $150 in bonus bets -- if their bet wins.

Sign up for FanDuel now!

Cavaliers vs. Bulls odds, spread and total

Cavaliers vs. Bulls how to watch 

  • Date: Wednesday, Feb. 28
  • Time: 8:00 p.m. EST
  • Venue: United Center
  • How to watch (TV): NBC Sports Chicago, Bally Sports Ohio
  • Cavs record: 38-19
  • Bulls record: 27-31

Cavaliers vs. Bulls injury reports

Cavaliers injury report

  • Not submitted yet

Bulls injury report

  • Not submitted yet

Cavaliers vs. Bulls key players to watch

Cleveland Cavaliers

Donovan Mitchell: Even though he shot just 8-for-21 in his last game against Chicago, Mitchell finished with 30 points in that meeting. The Bulls need to slow him down if they want a chance to win this game, although it’s possible that the Cavs sit a rotation player or two on the second night of a back-to-back

Chicago Bulls

Coby White: In his last meeting with the Cavs, White came up short on a game-tying 3-point shot, but he still had a strong game. The young guard scored 32 points on 5-of-8 shooting from 3 in that matchup, and he’s in the midst of a breakout season averaging 19.5 points, 4.7 rebounds and 5.2 assists per game. 

Cavaliers vs. Bulls prediction and pick

These teams have faced off three times this season, finishing with 204, 200 and 213 combined points in those games. 

Cleveland has won each matchup, including two wins by double digits, so I’m not sold on taking the Bulls in this game as five-point dogs – even though the team is an impressive 7-4-1 ATS as a home underdog this season. 

We could see some tired legs (and potentially some players ruled out) in this game on the second night of a back-to-back. 

The Bulls are 5-4 on the OVER on the second night of a back-to-back this season while Cleveland is 4-5, and the UNDER has hit in 11 of the Cavs’ 15 games as road favorites this season. 

Chicago profiles as a perfect UNDER team, playing at the No. 29 pace in the NBA, and the Cavs feature a top-10 defense on the season. 

Don’t be shocked if we see a slug fest between these two division rivals. 

Game odds refresh periodically and are subject to change.

Find Peter Dewey's NBA betting record here (futures included). You can also follow my daily plays on BetStamp here.